Significance of subjective symptoms and diagnostic criteria in initial forms of cerebral circulation insufficiency
Eninia GI, Purinia IV, Robule VKh,
Maiore IKh, Timofeeva TN, Berzina AIa.
Zh Nevropatol Psikhiatr Im S S Korsakova 1989;89(12):19-23
Piracetam was applied to the treatment of 60 patients with initial manifestations of brain circulation failure and stage I circulatory encephalopathy. The drug exerted a beneficial therapeutic effect by reducing high brain vascular resistance (both extra- and intracranial) and by increasing the lowered volume of pulse fluctuations. It made fibrinolytic blood activity and aggregation of formed elements of the blood return to normal. An appreciable anti-atherogenic effect was discovered as well. It should be taken into consideration that in patients with a dramatic lowering of pulse fluctuations, the use of piracetam in a dose of 1.6 g/day may enhance headache. In such cases the dose should be reduced.